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Mouse Hepatitis Virus (MHV)
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Mouse Hepatitis Virus (MHV)70.62 KB
Description
Mouse hepatitis virus (MHV) is probably the most important pathogen of laboratory mice.
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- Background: Mouse hepatitis virus is probably the most important pathogen of laboratory mice. Although the infection generally causes no overt clinical signs, it can cause profound changes in the immune system, affecting the interpretation of a wide variety of experimental results. It is an ssRNA virus of the family Coronaviridae. Approximately 25 strains or isolates of MHV have been described.
- Transmission: MHV is extremely contagious and is transmitted primarily via aerosol, direct contact, fomites, and, experimentally, via transplantable tumors and via the placenta.
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- Mice
- hepatitis
- mhv